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Laboratorio di Immunologia clinica e sperimentale

Attività di Ricerca Domenico Mavilio Publications
PUBBLICAZIONI SELEZIONATE
 
Gazzola P., Mavilio D., Costa P., Fogli M., Bruzzone B., Icardi G., Primavera A., Cocito L., De Maria A. Possible HCV involvement in acute meningoradiculitis/ polyradiculitis of HIV-1 coinfected patient.
AIDS 2001 March 1; 15(4): 539-541. Impact Factor: 6.881
 
De Maria A., Biassoni R., Fogli M., Rizzi M., Cantoni C., Costa P., Conte R., Mavilio D., Cafaro A., Moretta A., Moretta L. Identification, molecular cloning and functionalcharacterization of NKp46 and NKp30 Natural Cytotoxicity Receptors in MacacaFascicularis NK cells.
European Journal of Immunology 2001 December; 31(12): 3546-56. Impact Factor: 4.99
 
D. Mavilio*, J. Benjamin, M. Daucher, G. Lombardo, S. Kottilil, M.A. Planta, E. Marcenaro, C. Bottino, L. Moretta, A. Moretta, and A.S. Fauci. Natural Killer cells in HIV-1 Infection: Dichotomous effects of viremia on inhibitory and activating receptors and their functional correlates.
Proc Natl Acad Sci U S A. 2003 December 9;100(25):15011-6. Impact Factor: 10.896
 
Mavilio D.*, Lombardo G, Benjamin J, Kim D, Follman D, Marcenaro E, O'Shea MA, Kinter A, Kovacs C, Moretta A, Fauci AS. Characterization of CD56-/CD16+ natural killer (NK) cells: a highly dysfunctional NK subset expanded in HIV-infected viremic individuals.
Proc Natl Acad Sci U S A. 2005 February 22; 102(8):2886-91. Impact Factor: 10.231
 
Mavilio D.*, Benjamin J, Kim D, Lombardo G, Daucher M, Kinter A, Nies-Kraske E, Marcenaro E, Moretta A, Fauci AS. Identification of NKG2A and NKp80 as specific Natural Killer cell markers in rhesus and pig-tailed monkeys.
Blood 2005 September 1; 106: 1718-1725. Impact Factor: 10.131
 
Fauci A.S., Mavilio D., Kottilil S. NK cells in HIV infection; paradigm for protection or targets for ambush.
Nature Review Immunology 2005 November; 5 (11): 835-43. Impact Factor: 30.458
 
Mavilio D.*, Lombardo G., Kinter A., Fogli M., La sala A., Ortolano S., Farschi A., Follmann D., Gregg R., Kovacs C., Marcenaro E., Pende D., Moretta A., Fauci A.S. Characterization of the defective interaction between a subset of natural killer cells and dendritic cells in HIV-1 infection.
Journal of Experimental Medicine 2006 October 2; 203(10): 2239-2350. Impact Factor: 14.484
 
Ward J, Bonaparte M, Sacks J, Guterman J, Fogli M, Mavilio D, Barker E . HIV modulates the expression of ligands important in triggering natural killer cell cytotoxic responses on infected primary T-cell blasts.
Blood 2007 August 15; 110: 1207-1214. Impact Factor: 10.896
 
Fogli M.,  Mavilio D.* , Brunetta E., Varchetta S., Ata K., Roby G., Kovacs C., Follmann D., Pende D., Ward J., Barker E., Marcenaro E., Moretta A. and Fauci A.S. Lysis of endogenously infected CD4+ T cell blasts by rIL-2 activated autologous natural killer cells from HIV-infected viremic individuals.
PLos Pathogens 2008 July 11 ;4(7):e1000101. Impact Factor: 9.125
 
Varchetta S., Oliviero B., Donato F., Agnelli F., Rigamonti C., Paudice E., Arosio E., Berra M. Rossi G., Tinelli C., Colombo M., Mavilio D. and. Mondelli M.U. Prospective study of natural killer cell phenotype in recurrent hepatitis c virus infection following liver transplantation.
J. Hepatol. 2009 February; 50: 314–322. Impact Factor: 7.818
 
Oliviero B., Varchetta S., Paudice E., Michelone G., Zaramella M., Mavilio D., De Filippi F., Bruno S. and Mondelli M.U. Natural Killer Cell Functional Dichotomy in Chronic Hepatitis B and Chronic Hepatitis C Virus Infections.
Gastroenterology 2009 September; 137: 1151-1160. Impact Factor: 12.899
 
Brunetta E., Fogli M., Varchetta S, Bozzo L., Hudspeth K.L., Marcenaro E., Moretta A. and Mavilio D*. The decreased expression of Siglec-7 represents an early marker of dysfunctional Natural Killer cell subsets associated with high levels of HIV-1 viremia.
Blood 2009 October 29, 114(18): 3822-30. Impact Factor: 10.555
 
Brunetta E., Fogli M., Varchetta S, Bozzo L., Hudspeth K.L., Marcenaro E., Moretta A. and Mavilio D*. Chronic HIV-1 viremia reverses NKG2A/NKG2C ratio on Natural Killer cells in patients with HCMV co-infection.
AIDS 2010 January 2, 24: 27-34 . Impact Factor: 4.909
 
Brunetta E., Hudspeth K.L. and Mavilio D *. Pathologic Natural Killer cell subset redistribution in HIV-1 infection: new insights in pathophysiology and clinical outcomes.          
J. Leukocyte Biol. Epub ahead of print July 22, 2010 - DOI:10.1189/jlb.0410225 Impact Factor: 4.403
 
Gorini S., Callegari G., Romagnoli G., Mammi C., Mavilio D., Rosano G., Fini M.,  Di Virgilio F., Gulinelli S., Falzoni S., Ferrari D., and La Sala A. ATP secreted by endothelial cells blocks CX3CL1-elicited natural killer cell chemotaxis and cytotoxicity via P2Y11 receptor activation
Blood 2010 Epub ahead of print July 28, 2010 - DOI 10.1182/blood-2009-12-260828 Impact Factor: 10.555  
 
* Corresponding Author
 
 
 
CAPITOLI DI LIBRO
 
Natural Killer Cells, Basic Science and Clinic Application
First Edition 2010
Chapter 36: “Natural killer cells and human immunodeficency virus” by Domenico Mavilio*,
Anne Hosmalin, Daniel Scott-Algara.
Editore: Academic Press, Elsevier and Macmillan Publishing, Oxford, UK .

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